PATHOLOGIES

FOREFOOT CONDITIONS

Morton’s Neuroma (Interdigital Neuroma)

What is it?

Morton’s neuroma is a painful swelling or thickening of a digital nerve, usually between the 3rd and 4th toes (third intermetatarsal space). It is not a true tumor, but rather a benign enlargement of the nerve due to chronic irritation or compression.

CAUSES
  • Repetitive compression of the nerve, often due to:
    • Tight or narrow footwear (especially high heels)
    • Excessive forefoot loading during walking or running
  • Foot biomechanics:
    • Flatfoot or hyperpronation
    • High-arched (cavus) feet
    • Associated deformities like bunions or hammer toes
  • Burning, tingling, or numbness in the forefoot
  • Pain radiating into the toes (especially 3rd and 4th)
  • A sensation of “walking on a pebble” or “folded sock”
  • Symptoms often worsen with walking, tight shoes, or prolonged standing
  • Relief when removing shoes or massaging the foot
  • Clinical exam: Includes palpation of the intermetatarsal space, Mulder’s click test (palpable click when compressing forefoot)
  • Ultrasound or MRI: Can confirm nerve thickening or exclude other causes
  • Diagnostic injection: Local anaesthetic may help confirm the diagnosis and relieve symptoms

Non-Surgical

  • Footwear modification: Wider toe boxes, low heels
  • Metatarsal pads or custom orthotics to offload the nerve (not very effective)
  • Activity modification
  • NSAIDs to reduce inflammation
  • Corticosteroid injections – can provide temporary relief

Surgical

  • Considered if symptoms persist despite conservative treatment
  • Options:
    • Neurectomy – surgical removal of the affected nerve segment
    • Decompression – release of surrounding ligaments without nerve excision
  • Surgery typically has a high success rate, but may result in permanent numbness between the affected toes
  • Many patients improve with non-surgical care, especially with early diagnosis
  • Surgery is generally effective for persistent cases but carries risks of altered sensation